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Renal Corpuscle Cell Connectome

Renal corpuscle (also called malpighian body) is the blood filtration unit of the nephron of the kidney. It is composed of a knot of capillaries (glomerulus) surrounded by a double-walled capsule (Bowman's capsule) that opens into a tubule.

KPMP renal corpuscle human with labels graphic

Note: Above is a graphic of renal corpuscle. Click the image or Here to see an enlarged image. Copyright: KPMP (Kidney Precision Medicine Project).

Renal corpuscle connectome cell composition:

As shown in the above image, renal corpuscle connectome consists of the following cells and associated components:

Locations (from UBERON)

    Kidney (UBERON_0002113), more specifically, kidney nephron (UBERON_0001285).

Lineage

    The kidney, including the kidney epithelial cells, arises from OSR1+ mesenchymal progenitor cells in the intermediate mesoderm. Ref: Shankland et al., 2014.

Biological Processes (from GO)

    Renal corpuscle has the following associated functions:

Images

    More to add. Stay tuned ...

References

 

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